Resources for COVID-19 Randomized Clinical Trial Design

Vanderbilt Institute for Clinical and Translational Science
Research Methods Program
Department of Biostatistics
Vanderbilt University School of Medicine
Nashville TN USA

Topic Section
Ordinal outcomes in clinical trials 3.6 and 5.12.5
Proportional odds model 7.6
Power calculations tailored to the proportional odds model 7.8.3
Bayesian approach for a single mean 5.6.2
Bayesian logistic model 6.10.3
Bayesian two-sample t-test 5.9.3 and 5.10.5
Analysis plan for differential treatment effect (heteroeneity of treatment effect) and why subgroup analysis should be avoided 13.6
Covariate adjustment in RCTs Chapter 13
Overview of branches of statistics 5.3
Problems with p-values 5.4

Vanderbilt Department of Biostatistics