An Improved Nonlinear Imputation/Transformation Method; Biometric Society – ENAR (12Apr94, PDF)
Analysis of Cost Data; DIA Meeting on Economic Assessment in Clinical Trials, Hilton Head SC (6Nov97, PDF)
Problems with Surgical Report Cards; U. of Virginia Surgical Grand Rounds, 25Mar98 (23Mar98, PDF)
The Role of Covariable Adjustment in the Analysis of Clinical Trials; Henry Stewart Conference on Statistics of Multi-Center Trials, Washington DC, Paul Gallo, Chair, 14Sep01 (PDF).
Regression Modeling and Pre-modeling Strategies; Joint Statistics and Biostatistics Seminar, University of Washington, Seattle, 18May1998; Seminar, Department of Epidemiology & Biostatistics, Memorial Sloan-Kettering Cancer Center, 14Sep1998; Seminar, Division of Quantitative Psychology, University of Virginia, 3Dec98; Workshop, Division of Biostatistics, Stanford University, 14Jan1999; Seminar, Center for Statistical Sciences, Brown University, 10May99; Seminar, Case Western Reserve University at MetroHealth Medical Center, 14Jan00; Seminar, Merck & Co./New Jersey and Princeton-Trenton Chapters of ASA (Joseph L. Ciminera Seminar Series), 14Mar01; Seminar, Dept. of Biostatistics, Medical College of Virginia of Virginia Commonwealth University, 26Oct01 (updated 23Oct01, PDF). Click here to see some of the S-Plus commands used in the interactive demonstration part of this talk.
Directions in Statistical Methodology for Multivariable Predictive Modeling; Survival Analysis and Maximum Likelihood Techniques as Applied to Physiological Modeling Workshop, Undersea & Hyperbaric Medical Society Annual Scientific Meeting, Seattle, WA, 19May98 (PDF)
Model Uncertainty, Penalization, and Parsimony; International Society for Clinical Biostatistics (ISCB-19), Dundee, Scotland, 25Aug1998; Statistics / Biostatistics Colloquia U. Virginia, 20Nov1998; Updated and given to Department of Biostatistics, Johns Hopkins University, 17Jan01 (PDF). Click here for S-PLUS code.
How to Present Results of Regression Models to Clinicians. Seminar, Department of Biomedical Informatics, Ljubljana University, Ljubljana, Slovenia, Janez Stare, Organizer; September 1999.
Experiences in Teaching S-PLUS. Invited presentation, 1999 S-PLUS International User Conference, New Orleans, LA 21Oct99 (PDF).
A Graphical User Interface Builder for Data Entry and Regression Model Prediction using Windows/NT S-PLUS. Invited presentation, 1999 S-PLUS International User Conference, New Orleans, LA 20Oct99 (PDF). Click here to see screen shot for last example (PNG graphic file). Click here to see documentation for the Dialog function.
Dilemmas in Regression Modeling. University of Virginia Statistics/Biostatistics Colloquium, 5Nov99 (PDF). Click here to obtain S-PLUS code used to do the analyses and simulations presented in this talk.
Semiparametric Modeling of Health Care Cost and Resource Utilization. Contributed presentation, 1999 International Conference on Health Policy Research, Santa Monica, California, 3Dec99, updated 6Mar00, 9May01. Also presented at the 24th Annual Midwest Biopharmaceutical Statistics Workshop, Muncie Indiana, 23May01 (PDF). Click here for S code used for the analyses presented. Click here for documentation of S-PLUS areg.boot and related functions.
Measurement, Statistical Consulting, and Computing Issues. Seminar given at the SmithKline Beecham Biometrics Advisory Board Meeting, 1Dec00 (PDF). Click herefor the full paper.
Statistical Issues in Medical Research and Medical Decision-Making. Seminar presented at the Department of Radiology Research Conference, University of Virginia School of Medicine, 16Feb01 (PDF). Deals with limited role for hypothesis testing and P-values, bias and precision, how to present results, and respecting continuous variables.
On Designing a Web-Based Clinical Research Data Management System. Seminar presented to the Dept. of Health Evaluation Sciences Research Conference, UVa, 26Sep01.
Exploratory Analysis of Clinical Safety Data to Detect Safety Signals (Frank Harrell and Thomas Burgan). GlaxoSmithKline Biostatistics Advisory Board Meeting, Research Triangle Park NC, 29Oct02. Also presented at the Duke Clinical Research Institute Research Conference, 25Mar03, to Biometrics Research at Merck Research Labs, 20Aug03, as a contributed paper to the Society for Clinical Trials, 24May04, as an invited presentation for the Lincoln Technologies Data Visualization Workshop, 1Jul05, as an invited presentation for the FDA Visiting Professor Lecture Series, 11Oct05 and to the Department of Statistics, University of Glasgow, Scotland 8Jun06. For R code used to do the analyses and create graphics, click here (requires the Hmisc package for R).
Towards More Automated and Better Statistical Reporting for Clinical Trials. Seminar presented to the Dept. of Health Evaluation Sciences Research Conference, UVa, 13Nov02. Modified and presented to Biometrics Research at Merck Research Labs, 20Aug03. Modified and presented to the Department of Biostatistics, 2Jun04. Presented to the FDA Visiting Professor Lecture Series, 11Oct05. Expanded and improved format and renamed R for Clinical Trial Reporting: Reproducible Research, Quality and Validation and presented at useR! 2007, Ames IA 10 Aug 2007. See Rreport for more up-to-date information.
Statistical Principles to Live By. Invited presentation, Applied Statistics 2004 Conference, Slovenian Statistical Society, Ljubljana, Slovenia, 21Sep04. Modified and presented to the Department of Biostatistics, 13Oct04. Modified further and presented to the Department of Biostatistics, 5Jan05. Modified and presented to the Department of Biostatistics, Bioinformatics and Epidemiology, Medical University of South Carolina, Charleston, 13Feb06, Duke Clinical Research Institute 2 Jun 2006, Department of Statistics, Napier University, Edinburgh, Scotland 9 Jun 2006, at useR!:The R User Conference, Vienna, 17 Jun 2006, Vanderbilt Kennedy Center, 25 Oct 2006, and Department of Psychology and Human Development, Peabody College, Vanderbilt University 12 Jan 2007, to the Division of Biostatistics, Department of Preventive Medicine, Northwest University School of Medicine, 23 Apr 2007, to the National Library of Medicine, 3 Aug 2007, and to the Division of Biostatistics, Medical College of Wisconsin, Milwaukee, 22 May 2008.
A Good P-value is Hard to Find: Why I’m a Bayesian When Time Allows, Seminar presented to the Department of Biostatistics, University of Michigan, 19Sep97, to the Department of Biostatistics, Vanderbilt University, 2Mar05, and to the Middle Tennessee Chapter of the ASA, Nashville, 26Apr07.
Criteria for Building and Selecting Optimal Risk Models. Invited presentation, Defining Risk in Acute Coronary Syndrome: The Gateway to Enhancing Cardiovascular Care / Statistical Issues in Risk Models. Washington DC 2-4 June 2005.
Developing and Validating Prognostic Models for Health Outcomes using Modern Analytical Tools. Invited presentations, University College London Medical School and Department of Statistical Science 12Jun06 and Department of Epidemiology, Torino University, Torino, Italy 14Jun06; Department of Biostatistics, Vanderbilt University, 12Jul06. Abstract | R Code
Statistical Methods and Statistical Pitfalls in Biomarker Research; see also here. Presented at the Vanderbilt University Biomarker Research Summit 22Jun07 and to the Department of Biostatistics 4Jun08.
